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Vinagolu Rajasekhar K Cancer Stem Cells - anarbaev.ru
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Vinagolu Rajasekhar K. Cancer Stem Cells


Cancer Stem Cells covers a wide range of topics in cancer stem cell biology, including the functional characteristics of cancer stem cells and how they're generated, where they are localized, the means by which cancer stem cells can be targeted, and how cancer stem cells can be reprogrammed back to normal tissue stem cells. Each chapter begins with a brief historical note and concept summary, followed by a description of the latest basic or clinical advance associated with the topic. Cancer Stem Cells builds systematically from coverage of the basic research stage to an advanced research level, from clinical relevance to therapeutic potential, and will be a valuable resource for professionals in the fields of cancer research and stem cell biology.

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Sharmila Bapat A. Cancer Stem Cells. Identification and Targets


Because the concept and discoveries of cancer stem cells are relatively new, scientists and researchers need an introduction to this dynamic area. Cancer Stem Cells presents a consolidated account of the research done to date and recent progresses in the studies of cancer stem cells. Such a presentation facilitates a better understanding of and draws attention to stem cell and cancer biology – two fields that enhance, move, and evolve into each other continuously. It provides an informative study in designing approaches to apply stem cell principles to cancer biology while offering an overview of the challenges in developing combination stem and cancer biology targets for therapeutics. This book serves as a primer for new researchers in the field of cancer biology.

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Tarik Regad Principles of Stem Cell Biology and Cancer


Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics Tarik Regad, The John van Geest Cancer Research Centre, Nottingham Trent University, UK, Thomas J. Sayers, Centre for Cancer Research, National Cancer Institute, Frederick, USA and Robert Rees The John van Geest Cancer Research Centre, Nottingham Trent University, UK The field of cancer stem cells is expanding rapidly, with many groups focusing on isolating and identifying cancer stem cell populations. Although some progress has been made developing efficient cancer therapies, targeting cancer stem cells remains one of the important challenges facing the growing stem cell research community. Principles of Stem Cell Biology and Cancer brings together original contributions from international experts in the field to present the very latest information linking stem cell biology and cancer. Divided into two parts, the book begins with a detailed introduction to stem cell biology with a focus on the characterization of these cells, progress that has been made in their identification, as well as future therapeutic applications of stem cells. The second part focuses on cancer stem cells and their role in cancer development, progression and chemo-resistance. This section of the book includes an overview of recent progress concerning therapies targeting cancer stem cells. Features: An authoritative introduction to the link between stem cell biology and cancer. Includes contributions from leading international experts in the field. Well-illustrated with full colour figures throughout. This book will prove an invaluable resource for basic and applied researchers and clinicians working on the development of new cancer treatments and therapies, providing a timely publication of high quality reviews outlining the current progress and exciting future possibilities for stem cell research.

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Rob Burgess Stem Cells


Stem Cells: A Short Course is a comprehensive text for students delving into the rapidly evolving discipline of stem cell research. Comprised of eight chapters, the text addresses all of the major facets and disciplines related to stem cell biology and research. A brief history of stem cell research serves as an introduction, followed by coverage of stem cell fundamentals; chapters then explore embryonic and fetal amniotic stem cells, adult stem cells, nuclear reprogramming, and cancer stem cells. The book concludes with chapters on stem cell applications, including the role of stem cells in drug discovery and therapeutic applications in spinal cord injury, brain damage, neurological and autoimmune disorders, among others. Written by a leader in the field, Stem Cells: A Short Course appeals to both students and instructors alike, appealing to academic enthusiasm for stem cell research and applications.

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Khalid Shah Stem Cell Therapeutics for Cancer


Stem Cell Therapeutics for Cancer covers the application of stem cells in various cancers, with an emphasis on the aspects of these strategies that are critical to the success of future stem cell-based therapies for cancer. Topics covered in the book include stem cell sources, tumor specificity, targeted therapeutics, visualizing the stem cell, and therapeutic agent pharmacokinetics. Each chapter contains a brief introduction to the cancer, followed by an exploration of how engineered stem cells have been utilized to cure the disease in mouse models and in early phase clinical trials. Comprises of sections on stem cell therapy in brain cancers, lung cancers, breast cancers, as well as stem cells in combination with other therapies Focuses on the practical applications of using stem cells as gene delivery agents to treat cancer Includes coverage of cutting-edge molecular imaging techniques in stem cell therapeutics for a variety of tumour types

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Heide Schatten Cell and Molecular Biology and Imaging of Stem Cells


Cell and Molecular Biology and Imaging of Stem Cells features original and review articles written by experts who have made significant contributions to stem cell biology and imaging. Chapters cover a broad spectrum of aspects of the field, including Stem cells from the Amniotic Fluid and Placenta, Biomaterials as Artificial Niches for Pluripotent Stem Cell Engineering, Low-Intensity Ultrasound in Stem Cells and Tissue Engineering, Mammalian Neo-Oogenesis from Ovarian Stem Cells, Oct4-EGFP Transgenic Pigs as a New Tool for Visualization of Pluripotent and Reprogrammed Cells, Regulation of Adult Intestinal Stem Cells, Stem Cell Therapy for Veterinary Orthopedic Lesions, Sex Steroid Combinations in Regenerative Medicine for Brain and Heart Diseases, Hair Follicle Stem Cells, The Potential of Using Induced Pluripotent Stem Cells in Skin Diseases, Mitochondrial Differentiation in Early Embryo Cells and Pluripotent Stem Cells, and The Role of Centrosomes in Cancer Stem Cell Functions. Cell and Molecular Biology and Imaging of Stem Cells addresses a wide variety of cell and molecular topics in unprecedented detail, and is a must-read for graduate students and academic and industry professionals in the expanding field of stem cell biology. Reviews new imaging tools and markers for cell and molecular imaging in stem cell biology. Covers novel aspects of stem cell imaging in reproductive biology and stem cell niches Includes chapters on the developing area of centrosome biology as it applies to embryonic and adult stem differentiation

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Группа авторов Applications of Flow Cytometry in Stem Cell Research and Tissue Regeneration


A much-needed primer on the use of laser flow cytometry for stem cell analysis Laser flow cytometry is a powerful tool for rapid analysis of cells for marker expression, cell cycle position, proliferation, and apoptosis. However, no resources specifically address the use of this methodology for the study of stem cells; this is especially important as stem cell analysis involves specialized methods and staining procedures based on specific characteristics such as marker expression, cell size, drug transport, and efflux of the stem cells. Now, this book reviews these procedures, discusses the science behind them, and provides real-world examples to illustrate the usefulness of the methods. It brings together world-class experts in pathology, biophysics, immunology, and stem cell research, who draw upon their extensive experience with the methods and show examples of good data to help guide researchers in the right direction. Chapter coverage includes: Stem cell analysis and sorting using side population Flow cytometry in the study of proliferation and apoptosis Stem cell biology and application Identification and isolation of very small embryonic-like stem cells from murine and human specimens Hematopoietic stem cells—issues in enumeration Human embryonic stem cells: long-term culture and cardiovascular differentiation Limbal stem cells and corneal regeneration Flow cytometric sorting of spermatogonial stem cells Breast cancer stem cells Stem cell marker expression in cells from body cavity fluids This book is an essential resource for all graduate students, practitioners in developing countries, libraries and book repositories of universities and research institutions, and individual researchers. It is also of interest to laboratories engaged in stem cell research and use of stem cells for tissue regeneration, and to any organization dealing in stem cell and tissue regeneration research.

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Uma Lakshmipathy Emerging Technology Platforms for Stem Cells


This book focuses on practical applications for using adult and embryonic stem cells in the pharmaceutical development process. It emphasizes new technologies to help overcome the bottlenecks in developing stem cells as therapeutic agents. A key reference for professionals working in stem cell science, it presents the general principles and methodologies in stem cell research and covers topics such as derivitization and characterization of stem cells, stem cell culture and maintenance, stem cell engineering, applications of high-throughput screening, and stem cell genetic modification with their use for drug delivery.

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Группа авторов Perinatal Stem Cells


Perinatal Stem Cells, 2nd Edition builds on the first edition to provide an updated tutorial on perinatal stem cells, including stem cells harvested from the amniotic fluid, placenta, maternal blood supply, umbilical cord and Wharton's Jelly. As in the first edition, coverage includes the underlying biology of each of the sources of pregnancy related stem cells, cell culture, and potential therapeutic uses, as well as insights on the impact of these stem cells from obstetricians and gynecologists, cardiologists, hematologists, tissue engineers, and cord blood bankers. Normally discarded as medical waste, perinatal stem cells offer a powerful therapeutic tool box alternative to the controversial embryonic stem cells. Since publication of the first edition, a burgeoning commerical industry has developed around various sources of perinatal cells, and the second edition now includes an overview of this growing industry. With contributions from some of the top academic stem cell laboratories in the United States as well as new chapters from international stem cell scientists, Perinatal Stem Cells presents an update on the cutting-edge research in the field while maintaining its signature clinical focus.

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Thyagarajan Bhaskar Primary and Stem Cells. Gene Transfer Technologies and Applications


This book describes basic cell engineering methods, emphasizing stem cell applications, and use of the genetically modified stem cells in cell therapy and drug discovery. Together, the chapters introduce and offer insights on new techniques for engineering of stem cells and the delivery of transgenes into stem cells via various viral and non-viral systems. The book offers a guide to the types of manipulations currently available to create genetically engineered stem cells that suit any investigator's purpose, whether it's basic science investigation, creation of disease models and screens, or cells for therapeutic applications.

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Vinagolu RAJASEKHAR | Senior Research Scientist | Doctor ...

Vinagolu Rajasekhar Nahum Sonenberg Translational control plays a pivotal role in the regulation of the pluripotency network in embryonic stem cells, but its effect on reprogramming somatic cells...

‪Vinagolu K. Rajasekhar‬ - ‪Google Scholar‬

‪Memorial Sloan Kettering Cancer Center‬ - ‪Cited by 6,324‬ - ‪Cell of Origin in Human Cancer‬ - ‪Tumor heterogeneity and Metstatic Tumor Evolution‬ - ‪Humanizing PDX Models‬

Loop | Vinagolu K. Rajasekhar

Vinagolu K. Rajasekhar. Doctorate. Memorial Sloan Kettering Cancer Center, Weill Cornell Graduate School of Medical Sciences, Cornell University. New York, United States. Vinagolu Rajasekhar. Overview; Bio; Network 20; Publications 38; Editorial Contributions 0; Impact-Total Views -Profile Views-Total Publications- ...

Vinagolu K. Rajasekhar, MSc., MPhil., PhD - Senior ...

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Cancer Stem Cells (eBook, PDF) von Vinagolu K. Rajasekhar ...

Cancer Stem Cells covers a wide range of topics incancer stem cell biology, including the functional characteristicsof cancer stem cells and how theyre generated, where they arelocalized, the means by which cancer stem cells can be targeted,and how cancer stem cells can be reprogrammed back to normal tissuestem cells.

Regulatory Networks in Stem Cells | Vinagolu K. Rajasekhar ...

Rajasekhar, Vinagolu K. Preview Buy Chapter 25,95 € Signaling Pathways in Embryonic Stem Cells. Pages 293-308. Reynolds, D. (et al.) Preview Buy Chapter 25,95 € Regulation of Stem Cell Systems by PI3K/Akt Signaling. Pages 309-318. Kimura, Tohru (et al.) Preview Buy Chapter 25,95 € Endothelial Ontogeny During Embryogenesis: Role of Cytokine Signaling Pathways. Pages 319-328. James, Daylon ...

Cancer Stem Cells by Vinagolu K. Rajasekhar

Cancer Stem Cells book. Read reviews from world’s largest community for readers. Cancer Stem Cells covers a wide range of topics in cancer stem cell biol...

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Vinagolu K. Rajasekhar (Author of Cancer Stem Cells)

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Dr. Vinagolu K. Rajasekhar, a Senior Research Scientist at the Memorial Sloan-Kettering Cancer Center, has been developing humanized patient derived xenograft (PDX) models of metastatic cancers in the institutional collaboration with Dr. John Healey, the Chief of Orthopedics Service.

Cancer Stem Cells: Rajasekhar, Vinagolu K.: 9781118356166 ...

In this beautiful book, Dr. Vinagolu K. Rajasekhar (Memorial Sloan Kettering Cancer Center - New York) thoughtfully weaved together the perspectives and contributions from several of the leading scientists in the field. This book is both an elegant review and a practical guide to the exciting, ...

9781118356166 - CANCER STEM CELLS by Vinagolu K Rajasekhar

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Multifaceted regulation of somatic cell reprogramming by ...

Soroush Tahmasebi 1 , Tommy Alain 2 , Vinagolu K Rajasekhar 3 , Jiang-Ping Zhang 4 , Masha Prager-Khoutorsky 5 , Arkady Khoutorsky 1 , Yildirim Dogan 6 , Christos G Gkogkas 7 , Emmanuel Petroulakis 1 , Annie Sylvestre 1 , Mohammad Ghorbani 4 , Sarah Assadian 1 , Yojiro Yamanaka 8 , Julia R Vinagolu-Baur 6 , Jose G Teodoro 1 , Kitai Kim 6 , Xiang-Jiao Yang 9 , Nahum Sonenberg 10

Cancer Stem Cells 1, Rajasekhar, Vinagolu K. - Amazon.com

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Concise Review: Roles of Polycomb Group Proteins in ...

Vinagolu K Rajasekhar et al. Stem Cells. 2007 Oct. Free article Show details Stem Cells Actions. Search in PubMed Search in NLM Catalog Add to Search . 2007 Oct;25(10):2498-510. doi: 10.1634/stemcells.2006-0608. Epub 2007 Jun 28. Authors Vinagolu K Rajasekhar 1 , Martin Begemann. Affiliation 1 Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, Rockefeller Research Laboratories, Room ...

Cancer Stem Cells - Vinagolu K Rajasekhar - Bok ...

In this beautiful book, Dr. Vinagolu K. Rajasekhar (Memorial Sloan Kettering Cancer Center - New York) thoughtfully weaved together the perspectives and contributions from several of the leading scientists in the field. This book is both an elegant review and a practical guide to the exciting, and still largely uncharted, world of cancer stem cells . I praise the editor and the authors for ...

Cancer Stem Cells eBook: Rajasekhar, Vinagolu K.: Amazon ...

by Vinagolu K. Rajasekhar (Author) Format: Kindle Edition. See all formats and editions Hide other formats and editions. Amazon Price New from Used from Kindle Edition "Please retry" £144.40 — — Hardcover "Please retry" £152.00 . £117.00: £119.10: Kindle Edition £144.40 Read with Our Free App Hardcover £152.00 2 Used from £119.10 8 New from £117.00 Cancer Stem Cells covers a wide ...

WikiGenes - Vinagolu K. Rajasekhar

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Regulatory Networks in Stem Cells (Stem Cell Biology and ...

by Vinagolu K. Rajasekhar (Editor) See all formats and editions Hide other formats and editions. Price New from Used from Kindle "Please retry" $252.57 — — Hardcover "Please retry" $265.86 . $265.84: $83.97: Paperback "Please retry" $297.07 . $297.07 — Kindle $252.57 Read with Our Free App Hardcover $265.86 7 Used from $83.97 4 New from $265.84 Paperback $297.07 11 New from $297.07 Stem ...

Regulatory Networks in Stem Cells - Vinagolu K Rajasekhar ...

Stem cells appear to be fundamental cellular units associated with the origin of multicellular organisms and have evolved to function in safeguarding the cellular homeostasis in organ t- sues. The characteristics of stem cells that distinguish them from other cells have been the fascinating subjects of stem cell research. The important properties of stem cells, such as ma- tenance of ...

Cancer Stem Cells Rajasekhar Vinagolu K

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Dr. V.K. Rajasekhar, M.Sc., M.Phil., Ph.D., is a Senior Research Scientist at Memorial Sloan-Kettering Cancer Center, New York. His work with patient derived prostate cancer stem cell xenografts, a first study in renewable Biobanking of these clinically relevant cells, has garnered eclectic post-publication reviews. Dr. Rajasekhar has received competitive research awards from the Alexander von ...

Vinagolu K. Rajasekhar | LibraryThing

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RNA G-quadruplexes cause eIF4A-dependent oncogene ...

author = "Wolfe, {Andrew L.} and Kamini Singh and Y. Zhong and Philipp Drewe and Rajasekhar, {Vinagolu K.} and Sanghvi, {Viraj R.} and Mavrakis, {Konstantinos J.} and Man Jiang and Roderick, {Justine E.} and {Van der Meulen}, Joni and Schatz, {Jonathan H.} and Rodrigo, {Christina M.} and Chunying Zhao and Pieter Rondou and {de Stanchina}, Elisa and Julie Teruya-Feldstein and Kelliher ...

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Pasquale Sansone, Vinagolu K. Rajasekhar, and Jacqueline Bromberg. Section V Novel and Potential Targets in Cancer Stem Cells 295. 23 Targeting Cancer Stem Cells—Modulating Embryonic Stem Cell Signaling, Epigenetics, and Tumor Metabolism 297 Naoko Takebe, Pamela Jo Harris, Yutaka Kondo, Abhilasha Nair, S. Percy Ivy, and Hideyuki Saya . 24 Oct4, Oct1, and Cancer Stem Cells 319 Jessica Maddox ...

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Molecular Insights into the Function, Fate, and Prospects ...

Vinagolu K. Rajasekhar, Department of Surgery, Memorial Sloan‐Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA. Telephone: 212‐639‐8510; Fax: 212‐717‐3627 Telephone: 212‐639‐8510; Fax: 212‐717‐3627

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Regulatory Networks in Stem Cells by Vinagolu K ...

Stem cells appear to be fundamental cellular units associated with the origin of multicellular organisms and have evolved to function in safeguarding the cellular homeostasis in organ t- sues. The characteristics of stem cells that distinguish them from other cells have been the fascinating...

Ghent University Academic Bibliography

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Anti-tumor effects of an Id antagonist with no acquired ...

Id proteins are helix-loop-helix (HLH) transcriptional regulators frequently overexpressed in cancer. Id proteins inhibit basic HLH transcription factors through protein-protein interactions, often inhibiting differentiation and sustaining proliferation. We recently identified a small-molecule, AGX51, which targets Id proteins for degradation and impairs ocular neovascularization in mouse models.

Tumour-initiating stem-like cells in human prostate cancer ...

This article is from Nature Communications, volume 2.AbstractAndrogen depletion is a key strategy for treating human prostate cancer, but the presence of...

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Thesleff Irma Stem Cells in Craniofacial Development and Regeneration


Stem Cells, Craniofacial Development and Regeneration is an introduction to stem cells with an emphasis on their role in craniofacial development. Divided into five sections, chapters build from basic introductory information on the definition and characteristics of stem cells to more indepth explorations of their role in craniofacial development. Section I covers embryonic and adult stem cells with a focus on the craniofacial region, while sections II-IV cover the development and regeneration of craniofacial bone, tooth, temporomandibular joint, salivary glands and muscle. Concluding chapters describe the current, cutting-edge research utilizing stem cells for craniofacial tissue bioengineering to treat lost or damaged tissue. The authoritative resource for dentistry students as well as craniofacial researchers at the graduate and post-graduate level, Stem Cells, Craniofacial Development and Regeneration explores the rapidly expanding field of stem cells and regeneration from the perspective of the dentistry and craniofacial community, and points the way forward in areas of tissue bioengineering and craniofacial stem cell therapies.

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Jonathan M. W. Slack The Science of Stem Cells


Introduces all of the essential cell biology and developmental biology background for the study of stem cells This book gives you all the important information you need to become a stem cell scientist. It covers the characterization of cells, genetic techniques for modifying cells and organisms, tissue culture technology, transplantation immunology, properties of pluripotent and tissue specific stem cells and, in particular, the relevant aspects of mammalian developmental biology. It dispels many misconceptions about stem cells—especially that they can be miracle cells that can cure all ills. The book puts emphasis on stem cell behavior in its biological context and on how to study it. Throughout, the approach is simple, direct, and logical, and evidence is given to support conclusions. Stem cell biology has huge potential for advancing therapies for many distressing and recalcitrant diseases, and its potential will be realized most quickly when as many people as possible have a good grounding in the science of stem cells. Content focused on the basic science underpinning stem cell biology Covers techniques of studying cell properties and cell lineage in vivo and in vitro Explains the basics of embryonic development and cell differentiation, as well as the essential cell biology processes of signaling, gene expression, and cell division Includes instructor resources such as further reading and figures for downloading Offers an online supplement summarizing current clinical applications of stem cells Written by a prominent leader in the field, The Science of Stem Cells is an ideal course book for advanced undergraduates or graduate students studying stem cell biology, regenerative medicine, tissue engineering, and other topics of science and biology.

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Stephen Sullivan Human Embryonic Stem Cells


With this valuable practical guide, three members of the Harvard Stem Cell Institute have compiled and edited the definite handbook for the exciting new field of human embryonic stem cell research. The editors have gathered protocols from scientists with extensive reputation and expertise, describing and comparing currently used techniques for the culture of human stem cells and discussing the strengths and weaknesses of the different approaches. Human Embryonic Stem Cells: The Practical Handbook contains the first centralised collection of methods used in human embryonic stem cell biology. The book covers the derivation of human stem cell lines, the obtaining of cells from human stem cell banks, the culturing and characterisation of the cells, and the differentiation of the cells in vitro and in vivo. Lastly, almost all of these protocols can also be used for analyzing and manipulating induced pluripotency iPS stem cells. This allows an even greater number of opportunities for those interested in purusing work in pluripotent stem cells, disease modelling, and other aspects of basic regenerative medicine research. The novel and useful focus of this book sets it apart from other available books: Compares and evaluates the protocols used in leading laboratories working on human embryonic stem cells Centred solely on practical protocols for human (not mouse) embryonic stem cell research Includes extensive troubleshooting sections Addresses the different proclivities and behaviours of individual human embryonic cell lines Contains techniques currently known only to a small number of specialised laboratories worldwide This handbook represents an essential source of up-to-date practical information for all cell and developmental biologists working with human embryonic stem cells or wishing to enter the field. It is also essential reading for clinical researchers in areas such as diabetes, cardiovascular disease, and neurological diseases. Praise from the reviews: «…a highly readable and useful book… A notable feature of the book is its air of openness and honesty… This book… will help many to navigate the uncharted waters of human embryonic stem cell biology.» BRITISH SOCIETY FOR CELL BIOLOGY «… the imaginative solutions in this book can inspire us to get past our most frustrating limitations.» CELL STEM CELL «… the richness in the details of each protocol presented will certainly encourage more scientists to begin studies of Human pluripotent stem cells…» REGENERATIVE MEDICINE «In this fast-moving field, this [handbook] will help drive advances of more and more researchers.» DIFFERENTIATION «…a valuable resource for seasoned and novice researchers… an excellent addition to the reference collection of any medical library or research laboratory.» THE AMERICAN MEDICAL ASSOCIATION

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Группа авторов A Beginner's Guide to Targeted Cancer Treatments


The accessible guide to the principles behind new, more targeted drug treatments for cancer Written for anyone who encounters cancer patients, cancer data or cancer terminology, but have no more than a passing knowledge of cell biology. A Beginner's Guide to Targeted Cancer Treatments provides an understanding of how cancer works and the many new treatments available. Using over 100 original illustrations, this accessible handbook covers the biology and mechanisms behind a huge range of targeted drug treatments, including many new immunotherapies. Dr Vickers translates a complex and often overwhelming topic into something digestible and easily understood. She also explains what cancer is, how it behaves and how our understanding of cancer has changed in recent years. Each chapter takes the reader through how new cancer drugs work and their benefits and limitations. With the help of this book, readers will be able to better understand more complex, in-depth articles in journals and books and develop their knowledge. This vital resource: Offers the latest insights into cancer biology Provides a broad understanding of how targeted cancer treatments work Describes many of the new immunotherapy approaches to cancer treatment, such as checkpoint inhibitors and CAR-modified T cells Helps readers feel confident discussing treatment options with colleagues and patients Provides an overview of which treatments are relevant to each of the most common solid tumours and haematological cancers, and the rationale behind them Demystifies the jargon – terms such as the EMT, cancer stem cells, monoclonal antibodies, kinase inhibitors, angiogenesis inhibitors etc. Explains the resistance mechanisms to many new treatments, including issues such as the way cancer cells diversify and evolve and the complex environment in which they live

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Lakshmi Kiran Chelluri Stem Cells and Extracellular Matrices

Ronald R. Pethig Dielectrophoresis


Comprehensive coverage of the basic theoretical concepts and applications of dielectrophoresis from a world-renowned expert. Features hot application topics including: Diagnostics, Cell-based Drug Discovery, Sensors for Biomedical Applications, Characterisation and Sorting of Stem Cells, Separation of Cancer Cells from Blood and Environmental Monitoring Focuses on those aspects of the theory and practice of dielectrophoresis concerned with characterizing and manipulating cells and other bioparticles such as bacteria, viruses, proteins and nucleic acids. Features the relevant chemical and biological concepts for those working in physics and engineering

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Gregory Bock R. Stem Cells


Understanding stem cells at the molecular level is essential to understanding their behaviour in a physiological context. This volume in our acclaimed Novartis Foundation series features animated discussion from the world’s experts in this topic on the important ethical issues that are raised by research on stem cells. They review the various regulatory regimes, which apply in different countries – a key factor in determining where future stem cell research is carried out. Potential clinical applications covered in the book include the production of cardiomyocytes to replace damaged heart tissue, the production of insulin-producing cells for patients with diabetes, and the generation of neurons for the treatment of patients with Parkinson’s disease or spinal cord injury. Particular attention is paid to the factors that maintain stem cells in a pluripotent state or which drive them to create differentiated and lineage-committed cells in vitro and in vivo. Nuclear reprogramming, the process by which a nucleus acquires developmental potential, is covered here as well. It is relevant to stem cell research generally, and also to research on the cloning of animals by nuclear transfer. This book is an essential purchase for all those engaged in stem cell research, whether in the laboratory, the clinic or the regulatory authorities. From the reviews: «…this book provides: a comprehensive overview of current issues in stem cell research, with contributions from leading figures…» —BRITISH SOCIETY OF CELL BIOLOGY

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Группа авторов The Biology and Therapeutic Application of Mesenchymal Cells


The Biology and Therapeutic Application of Mesenchymal Cells comprehensively describes the cellular and molecular biology of mesenchymal stem cells and mesenchymal stromal cells, describing their therapeutic potential in a wide variety of preclinical models of human diseases and their mechanism of action in these preclinical models. Chapters also discuss the current status of the use of mesenchymal stem and stromal cells in clinical trials in a wide range of human diseases and disorders, for many of which there are limited, or no other, therapeutic avenues. • Provides coverage on both the biology of mesenchymal stem cells and stromal cells, and their therapeutic applications • Describes the therapeutic potential of mesenchymal stem and stromal cells in a wide variety of preclinical models of human diseases and their mechanism of action in these preclinical models • Discusses the current status of mesenchymal stem and stromal cells in clinical trials in a wide range of human diseases and disorders, for many of which there are limited, or no other, therapeutic avenues • Written and edited by leaders in the field The Biology and Therapeutic Application of Mesenchymal Cells is an invaluable resource for those studying stem cells, cell biology, genetics, gene or cell therapy, or regenerative medicine. About the Author Kerry Atkinson, MBBS MD DTM&H FRCP FRACP, is an Adjunct Professor at the University of Queensland Centre for Clinical Research in Brisbane, Australia, an Adjunct Professor in the Stem Cell Laboratories, Queensland University of Technology at the Translational Research Institute, Brisbane, Queensland, Australia and a Specialist in Internal Medicine at the Salisbury Medical Centre, Brisbane, Queensland, Australia.

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Группа авторов Wound Healing


A comprehensive resource on the recent developments of stem cell use in wound healing With contributions from experts in the field, Wound Healing offers a thorough review of the most recent findings on the use of stem cells to heal wounds. This important resource covers both the basic and translational aspects of the field. The contributors reveal the great progress that has been made in recent years and explore a wide range of topics from an overview of the stem cell process in wound repair to inflammation and cancer. They offer a better understanding of the identities of skin stem cells as well as the signals that govern their behavior that contributes to the development of improved therapies for scarring and poorly healing wounds. Comprehensive in scope, this authoritative resource covers a wealth of topics such as: an overview of stem cell regeneration and repair, wound healing and cutaneous wound healing, the role of bone marrow derived stems cells, inflammation in wound repair, role and function of inflammation in wound repair, and much more. This vital resource: Provides a comprehensive overview of stem cell use in wound healing, including both the basic and translational aspects of the field Covers recent developments and emerging subtopics within the field Offers an invaluable resource to clinical and basic researchers who are interested in wound healing, stem cells, and regenerative medicine Contains contributions from leading experts in the field of wound healing and care Wound Healing offers clinical researchers and academics a much-needed resource written by noted experts in the field that explores the role of stem cells in the repair and restoration of healing wounds.

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Группа авторов Micro and Nanotechnologies in Engineering Stem Cells and Tissues


A cutting-edge look at the application of micro and nanotechnologies in regenerative medicine The area at the interface of micro/nanotechnology and stem cells/tissue engineering has seen an explosion of activity in recent years. This book provides a much-needed overview of these exciting developments, covering all aspects of micro and nanotechnologies, from the fundamental principles to the latest research to applications in regenerative medicine. Written and edited by the top researchers in the field, Micro and Nanotechnologies in Engineering Stem Cells and Tissues describes advances in material systems along with current techniques available for cell, tissue, and organ studies. Readers will gain tremendous insight into the state of the art of stem cells and tissue engineering, and learn how to use the technology in their own research or clinical trials. Coverage includes: Technologies for controlling or regulating stem cell and tissue growth Various engineering approaches for stem cell, vascular tissue, and bone regeneration The design and processing of biocompatible polymers and other biomaterials Characterization of the interactions between cells and biomaterials Unrivaled among books of this kind, Micro and Nanotechnologies in Engineering Stem Cells and Tissues is the ultimate forward-looking reference for researchers in numerous disciplines, from engineering and materials science to biomedicine, and for anyone wishing to understand the trends in this transformative field.

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